PDGF Receptor alpha antibody [35248 (57/20)],Genetex,GTX42418

Host

Mouse

Reactivity

Human

Application

WB IHC-P ELISA

Conjugate

Unconjugated

Platform ID

BAB903835590

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePDGF Receptor alpha antibody [35248 (57/20)]
Cat. No.GTX42418
Gene ID (Entrez)5156
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P ELISA
ClonalityMonoclonal
Concentration1.0 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPDGFRA
ImmunogenPurified recombinant human platelet-derived growth factor (PDGF) receptor alpha (extracellular domain), derived from the insect cell line Sf21.
PurityProtein G purified
Appearance/FormLiquid
FormulationPBS, 5% Trehalose,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]

Synonyms

platelet derived growth factor receptor alpha , CD140A , PDGFR-2 , PDGFR2

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