PDGF Receptor alpha antibody [HL5000],Genetex,GTX645093

Host

Rabbit

Reactivity

Mouse

Application

ICC/IF

Conjugate

Unconjugated

Platform ID

BAB910721019

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NamePDGF Receptor alpha antibody [HL5000]
Cat. No.GTX645093
Gene ID (Entrez)5156
HostRabbit
IsotypeIgG
ReactivityMouse
ConjugationUnconjugated
ApplicationICC/IF
ClonalityMonoclonal
Concentrationbatch dependent (Please refer to the vial label for the specific concentration.)
TargetPDGFRA
ImmunogenRecombinant fragment of human PDGF Receptor alpha.
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]

Synonyms

platelet derived growth factor receptor alpha , CD140A , PDGFR-2 , PDGFR2

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