PDGF Receptor alpha antibody [N2C2], Internal,Genetex,GTX107903
Host
Rabbit
Reactivity
Human, Mouse, Rat
Application
WB ICC/IF
Conjugate
Unconjugated
Platform ID
BAB183568840

Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Specifications
Scientific Background
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq]
Synonyms
platelet derived growth factor receptor alpha , CD140A , PDGFR-2 , PDGFR2
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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