PE Anti-BACE1 antibody [027],Abcam,AB275651

Host

Rabbit

Reactivity

Human

Application

Flow Cyt (Intra)

Conjugate

PE

Platform ID

BAB482723797

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NamePE Anti-BACE1 antibody [027]
Cat. No.AB275651
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationPE
ApplicationFlow Cyt (Intra)
ClonalityMonoclonal
Clone Number027
ImmunogenRecombinant Fragment Protein within Human BACE1 aa 1-500. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.1% Sodium azide Constituents: 0.5% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (PubMed : 10656250, PubMed : 10677483, PubMed : 20354142). Cleaves CHL1 (By similarity). See full target information BACE1

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.