PE Anti-CD24 antibody [SN3],Abcam,AB77219

Purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Conjugate

PE

Platform ID

BAB546404480

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NamePE Anti-CD24 antibody [SN3]
Cat. No.AB77219
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationPE
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberSN3
PuritySize-exclusion chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide Constituents: 0.2% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells (PubMed : 11313396). In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity (By similarity). See full target information CD24

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