PE Anti-CEACAM5 antibody [CB30],Abcam,AB42796

ab42796 is a heavily glycosylated GPI anchored protein capable of heterophilic and homophilic adhesion and may play a role in metastasis of cancer cells. It is found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Conjugate

PE

Platform ID

BAB047553928

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NamePE Anti-CEACAM5 antibody [CB30]
Cat. No.AB42796
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationPE
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberCB30
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human CEACAM5.
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.1% Sodium azide Constituents: PBS, 0.5% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed : 10864933, PubMed : 10910050, PubMed : 2803308). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed : 2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed : 10910050).. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. See full target information CEACAM5

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