PE Anti-Calreticulin antibody [EPR3924] - ER Marker,Abcam,AB209577
What is this antibody validated in? PE Anti-Calreticulin antibody [EPR3924] - ER Marker (ab209577) is a rabbit recombinant monoclonal antibody and is validated for use in Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. Related products Antibody clone EPR3924 is also available pre-conjugated to a variety of labels for your convenience – Anti-Calreticulin PE [EPR3924] - ER Marker (ab209577). Other related products We have a range of other formats of antibody clone [EPR3924] also available for your convenience: ab92516 , HRP - ab195511 , Alexa Fluor® 488 - ab196158 , Alexa Fluor® 647 - ab196159 , PE - ab209577, Alexa Fluor® 405 - ab210431 , Carrier free - ab211962 , Carrier free - ab271865 , Alexa Fluor® 555 - ab275117 , Alexa Fluor® 594 - ab275343 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Human, Human, Mouse, Rat
Application
Flow Cyt (Intra), IHC-P, ICC/IF
Conjugate
PE
Platform ID
BAB108036147
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (PubMed : 7876246). Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (PubMed : 11149926). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity). See full target information CALR
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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