PE Anti-DR5 antibody [MD5-1],Abcam,AB95619
Host
Armenian hamster
Reactivity
Mouse
Application
Flow Cyt
Conjugate
PE
Platform ID
BAB174315582
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NamePE Anti-DR5 antibody [MD5-1]
Cat. No.AB95619
HostArmenian hamster
IsotypeIgG
ReactivityMouse
ConjugationPE
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberMD5-1
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenFull Length Protein corresponding to Mouse Tnfrsf10b. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS, 0.87% Sodium chloride
Storage+4°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. See full target information Tnfrsf10b
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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