PE Anti-Integrin alpha 2 antibody [AK7],Abcam,AB230470

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Conjugate

PE

Platform ID

BAB676264646

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NamePE Anti-Integrin alpha 2 antibody [AK7]
Cat. No.AB230470
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationPE
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberAK7
ImmunogenCell preparation containing ITGA2 protein. The exact immunogen used to generate this antibody is proprietary information.
PuritySize-exclusion chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.0975% Sodium azide Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.. (Microbial infection) Integrin ITGA2 : ITGB1 acts as a receptor for Human rotavirus A.. (Microbial infection) Integrin ITGA2 : ITGB1 acts as a receptor for Human echoviruses 1 and 8. See full target information ITGA2

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