PE Anti-Integrin alpha 2 antibody [DX5],Abcam,AB25493
NK cells cultured in the presence of IL2 progressively lose reactivity with DX5 as a consequence of cellular proliferation. Therefore, DX5 can be used to define functionally distinct subsets of murine NK cells. DX5 has not been demonstrated to have activating or blocking activity.
Host
Rat
Reactivity
Mouse
Application
Flow Cyt
Conjugate
PE
Platform ID
BAB988770893
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NamePE Anti-Integrin alpha 2 antibody [DX5]
Cat. No.AB25493
HostRat
IsotypeIgM
ReactivityMouse
ConjugationPE
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberDX5
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenCell preparation containing Itga2 protein. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.09% Sodium azide Constituents: PBS, 16% Sucrose
Storage+4°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Integrin alpha-2/beta-1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. It is also a receptor for laminins, collagen C-propeptides and E-cadherin. Mice homozygous for a null mutation in the alpha-2 die very early in embryogenesis. See full target information Itga2
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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