PE Anti-P-Selectin (CD62P) antibody [AK4],Abcam,AB119104

Host

Mouse

Reactivity

Human, Primates

Application

Flow Cyt

Conjugate

PE

Platform ID

BAB922091650

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NamePE Anti-P-Selectin (CD62P) antibody [AK4]
Cat. No.AB119104
HostMouse
IsotypeIgG1
ReactivityHuman, Primates
ConjugationPE
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberAK4
ImmunogenCell preparation containing SELP protein. The exact immunogen used to generate this antibody is proprietary information.
PuritySize-exclusion chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS, 0.2% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B : ITGB3) and integrin alpha-V/beta-3 (ITGAV : ITGB3) (PubMed : 37184585). See full target information SELP

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