PE Anti-PDE10A antibody [EPR22383],Abcam,AB318391

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . How are conjugated primary antibodies validated? This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling. For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

Antibody Labelling, Target Binding Affinity

Conjugate

PE

Platform ID

BAB553401120

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NamePE Anti-PDE10A antibody [EPR22383]
Cat. No.AB318391
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationPE
ApplicationAntibody Labelling, Target Binding Affinity
ClonalityMonoclonal
Clone NumberEPR22383
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides (PubMed : 10373451, PubMed : 10393245, PubMed : 16330539, PubMed : 17389385, PubMed : 27058447). Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate (PubMed : 10373451, PubMed : 10393245, PubMed : 17389385, PubMed : 27058447). May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition (PubMed : 27058447). See full target information PDE10A

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