PE Anti-Rat NKG2A/C/E Antibody anti-NKG2A/C/E - WEN28,BioLegend,250706

Host

Mouse

Reactivity

Rat

Application

FC -Quality tested

Platform ID

BAB851404447

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePE Anti-Rat NKG2A/C/E Antibody anti-NKG2A/C/E - WEN28
Cat. No.250706
HostMouse
RRIDAB_2728230 (BioLegend Cat. No. 250706)
IsotypeMouse IgG1, κ
ReactivityRat
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberWEN28
Concentration0.2 mg/ml
TargetNKG2A
ImmunogenRecombinant rat NKG2A-Fc fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

The NKG2 molecules are a family of lectin-like receptors that form heterodimers with CD94. NKG2/CD94 heterodimer are primarily expressed on NK cells, and a subset of CD8+T cells. Studies of CD94/NKG2 heterodimers on NK cells have demonstrated that the NKG2 components transduce signals after ligand binding.  NKG2A transduces inhibitory signals, while NKG2C and NKG2E transduce activating signals.

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