PE Anti-TLR3 antibody [40C1285.6],Abcam,AB45093

Host

Mouse

Reactivity

Human

Application

Flow Cyt (Intra)

Conjugate

PE

Platform ID

BAB055350184

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NamePE Anti-TLR3 antibody [40C1285.6]
Cat. No.AB45093
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationPE
ApplicationFlow Cyt (Intra)
ClonalityMonoclonal
Clone Number40C1285.6
Concentration0.16 - 0.69 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human TLR3 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. See full target information TLR3

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