PE Anti-beta 2 Microglobulin antibody [B2M-01],Abcam,AB49424

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Conjugate

PE

Platform ID

BAB295280020

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NamePE Anti-beta 2 Microglobulin antibody [B2M-01]
Cat. No.AB49424
HostMouse
IsotypeIgG2a
ReactivityHuman
ConjugationPE
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberB2M-01
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human B2M.
PuritySize-exclusion chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS, 0.2% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed : 25356553). See full target information B2M

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