PE/Cy5® Anti-CD40 antibody [1C10],Abcam,AB25044

This antibody closely resembles the gp39/CD40 ligand in its ability to stimulate proliferation of small, resting B lymphocytes in the absence of other cofactors. This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.

Host

Rat

Reactivity

Mouse

Application

IP, Flow Cyt, FuncS

Conjugate

PE/Cy5®

Platform ID

BAB548103664

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NamePE/Cy5® Anti-CD40 antibody [1C10]
Cat. No.AB25044
HostRat
IsotypeIgG2a
ReactivityMouse
ConjugationPE/Cy5®
ApplicationIP, Flow Cyt, FuncS
ClonalityMonoclonal
Clone Number1C10
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human CD40. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.1 Preservative: 0.09% Sodium azide Constituents: PBS, 16% Sucrose, 0.2% Gelatin
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Receptor for TNFSF5/CD40LG (PubMed : 31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity). See full target information CD40

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