PE/Cy7® Anti-CTLA4 antibody [UC10-4F10-11],Abcam,AB210384

The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Host

Armenian hamster

Reactivity

Mouse

Application

Flow Cyt (Intra)

Conjugate

PE/Cy7®

Platform ID

BAB236197129

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NamePE/Cy7® Anti-CTLA4 antibody [UC10-4F10-11]
Cat. No.AB210384
HostArmenian hamster
IsotypeIgG
ReactivityMouse
ConjugationPE/Cy7®
ApplicationFlow Cyt (Intra)
ClonalityMonoclonal
Clone NumberUC10-4F10-11
Concentration0.2 mg/mL Batch dependent concentration
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.09% Sodium azide Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor : the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. See full target information Ctla4

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