PE/Cyanine5 anti-rat CD161 antibody, CD161, 3.2.3,BioLegend,205612

3.2.3 recognizes a common epitope of NKR-1P1a (CD161a) and NKR-P1b (CD161b).

Host

Mouse

Reactivity

Rat

Application

FC - Quality tested

Platform ID

BAB179025964

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePE/Cyanine5 anti-rat CD161 antibody, CD161, 3.2.3
Cat. No.205612
HostMouse
RRIDAB_2894438 (BioLegend Cat. No. 205611)AB_2894438 (BioLegend Cat. No. 205612)
IsotypeMouse IgG1, κ
ReactivityRat
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number3.2.3
Concentration0.2 mg/mL
TargetCD161
ImmunogenLEW rat splenic NK cells
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Cyanine5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD161 is a 30 kD type II transmembrane C-type lectin, expressed as a homodimer. Rat NKR-P1 receptors are primarily expressed on NK cells, a subset of T cells, dendritic cells, and activated monocytes. There are three different types of NKR-P in rat, namely NKR-P1a, NKR-P1b, and NKR-P1c. NKR-P1a does not contain an ITIM structure and is an activating receptor, while NKR-P1b contains an ITIM and displays inhibitory function. LLT-1 (ligand lectin like transcript 1) is the ligand, while KLR (killer cell lectin like) functions as a receptor.

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