PE/Cyanine7 Rabbit anti-Mouse CD206/MMR mAb,ABclonal,A28361

Reactivity

Mouse

Application

FC (intra), FC

Conjugate

PE-Cy7. Ex:565nm. Em:778nm.

Platform ID

BAB425807452

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NamePE/Cyanine7 Rabbit anti-Mouse CD206/MMR mAb
Cat. No.A28361
RRID#N/A
IsotypeIgG
ReactivityMouse
ConjugationPE-Cy7. Ex:565nm. Em:778nm.
ApplicationFC (intra), FC
Working DilutionsFC (intra):≤0.5 µg per million cells in 100 µl volume
Clone NumberARC76673
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

Macrophage Mannose Receptor (MMR), also known as MR, is designated CD206, MRC1 (Mannose Receptor C-type 1), or CLEC13D (C-type Lectin Domain Family 13 Member D) due to its presence on cells beyond macrophages. CD206 is a 175 kDa endocytic receptor expressed on M2 selectively activated tissue macrophages, including tumor-associated macrophages (TAMs), inflammatory dendritic cells in specific lymphoid organs, and liver, spleen, lymphatic, and dermal microvascular endothelial cells.

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