PE/Cyanine7 Rabbit anti-Mouse CD223/LAG-3 mAb,ABclonal,A28466
Reactivity
Mouse
Application
FC
Conjugate
PE-Cy7. Ex:565nm. Em:778nm.
Platform ID
BAB563963634
ABclonal
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Product Specifications
Scientific Background
Specifications
NamePE/Cyanine7 Rabbit anti-Mouse CD223/LAG-3 mAb
Cat. No.A28466
RRID#N/A
IsotypeIgG
ReactivityMouse
ConjugationPE-Cy7. Ex:565nm. Em:778nm.
ApplicationFC
Working DilutionsFC:≤0.25 µg per million cells in 100 µl volume
Clone NumberARC77410
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only
Scientific Background
Enables MHC class II protein binding activity and transmembrane signaling receptor activity. Involved in negative regulation of regulatory T cell differentiation; plasmacytoid dendritic cell activation; and regulation of immune response. Acts upstream of or within cell surface receptor signaling pathway; negative regulation of interleukin-2 production; and positive regulation of natural killer cell mediated cytotoxicity. Located in external side of plasma membrane and extracellular region. Orthologous to human LAG3 (lymphocyte activating 3).
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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