PE/Cyanine7 anti-human CD143 Angiotensin-converting enzyme Antibody, CD143, 5-369,BioLegend,344208
Host
Mouse
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB375165565
BioLegend
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Product Specifications
Scientific Background
Specifications
NamePE/Cyanine7 anti-human CD143 Angiotensin-converting enzyme Antibody, CD143, 5-369
Cat. No.344208
HostMouse
RRIDAB_2783230 (BioLegend Cat. No. 344207)AB_2783231 (BioLegend Cat. No. 344208)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number5-369
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD143
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD143 (ACE, kininase II, peptidyl dipeptidase 1, peptidase P, carboxycathepsin) is a 171 kD, type I, single chain transmembranal metallopeptidase, whose cofactor is zinc. Its main targets are angiotensin I and bradykinin, acting as a blood pressure regulator. CD143 is expressed in endothelial cells; varying amounts of CD143 have been reported in different epithelial cells. The activation of macrophages and histiocytes induces the expression of this molecule.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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