PE/Cyanine7 anti-human Granzyme A Antibody anti-GranzymeA - CB9,BioLegend,507222

Additional reported applications (for the relevant formats) include: immunohistochemical staining3of formalin-fixed paraffin-embedded tissue sections, and immunoprecipitation2.

Host

Mouse

Reactivity

Human

Application

ICFC -Quality tested

Platform ID

BAB839821274

BioLegend

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePE/Cyanine7 anti-human Granzyme A Antibody anti-GranzymeA - CB9
Cat. No.507222
HostMouse
RRIDAB_2721667 (BioLegend Cat. No. 507221)AB_2721668 (BioLegend Cat. No. 507222)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationICFC -Quality tested
ClonalityMonoclonal
Clone NumberCB9
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetGranzyme A
ImmunogenPurified human Granzyme A
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Granzyme A is a 28 kD disulfide-linked homodimeric protein and the most abundant of the proteases occurring in CTL granules. It is homologous to other serine esterases, including other granyzmes, mast cell proteases, and neutrophil cathepsins. Granzyme B is thought to be a rapidly-acting apoptotic enzyme, while Granzyme A is slow acting. The CB9 monoclonal antibody recognizes human Granzyme A and has been shown to be useful for flow cytometry, immunoprecipitation, and immunohistochemistry (paraffin-embedded sections).

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