PE/Cyanine7 anti-human LGR5 (GPR49) Antibody, LGR5 (GPR49) , SA222C5,BioLegend,373807
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB638661555
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE/Cyanine7 anti-human LGR5 (GPR49) Antibody, LGR5 (GPR49) , SA222C5
Cat. No.373807
HostMouse
RRIDAB_2922590 (BioLegend Cat. No. 373807)AB_2922590 (BioLegend Cat. No. 373808)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberSA222C5
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetLGR5
ImmunogenHuman LGR5 transfectant cells
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
LGR5, also known as GPR49, is a 100 KD protein. It is a member of GPCR class A orphan receptor proteins which binds R-spondin and does not activate through heterotrimeric G protein like other GPCR. It triggers the Wnt signaling pathway downstream. LGR5 is expressed across a diverse range of tissue such as in the muscle, placenta, spinal cord and brain and particularly as a biomarker of adult stem cells in certain tissues.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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