PE/Cyanine7 anti-mouse CD103 Antibody, CD103, W19396D,BioLegend,110909
Clone W19396D can partially block binding of clone 2E7 on target cells.
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB646657715
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NamePE/Cyanine7 anti-mouse CD103 Antibody, CD103, W19396D
Cat. No.110909
HostRat
RRIDAB_2936717 (BioLegend Cat. No. 110909)AB_2936717 (BioLegend Cat. No. 110910)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberW19396D
Concentration0.2 mg/mL
TargetCD103
ImmunogenRecombinant mouse integrin alphaE/beta7
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD103 is the alpha E integrin, which forms a heterodimer with integrin beta 7. The heterodimer complex binds to E-cadherin. It is expressed in on T cells, notably in subpopulations in the lamina propria, on regulatory T cells, or resident memory T cells, and a subset of dendritic cells in gut mucosa. CD103 is thought to be involved with homing to intestinal epithelial sites and has been associated with high levels of TGF-beta presence.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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