PE/Cyanine7 anti-mouse CD319 Antibody, CD319, W19300I,BioLegend,118803

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB271370353

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePE/Cyanine7 anti-mouse CD319 Antibody, CD319, W19300I
Cat. No.118803
HostRat
RRIDAB_2941411 (BioLegend Cat. No. 118803)AB_2941411 (BioLegend Cat. No. 118804)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberW19300I
Concentration0.2 mg/mL
TargetCD319
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD319/CS1/CRACC/SLAMF7 (Signaling lymphocytic activation molecule family member7) is a 66 kD transmembrane protein belonging to the CD2 subset of the immunoglobulin superfamily. It is expressed on most and low or absent on monocytes and basophils.CD319 activates immune responses in NK cells when coupled with SAP-family adaptors (SAP, EAT-2, ERT) and inhibits immune responses in the absence of SAP-family adaptors or when bound to SH-domain molecules. CD319 is a self-ligand and homophilic interaction of CD319 regulates NK cell cytolytic activity. This mouse CD319 antibody does not show cross-reactivity with rat or human.

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