PE/Cyanine7 anti-mouse CD49a Antibody anti-CD49a - HMa1,BioLegend,142608

Additional reported applications (for the relevant format) include: inhibition of cell adhesion and cytokine production1,2.

Host

Armenian Hamster

Reactivity

Mouse

Application

FC -Quality tested

Platform ID

BAB361360930

BioLegend

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePE/Cyanine7 anti-mouse CD49a Antibody anti-CD49a - HMa1
Cat. No.142608
HostArmenian Hamster
RRIDAB_2749930 (BioLegend Cat. No. 142607)AB_2749931 (BioLegend Cat. No. 142608)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberHMα1
Concentration0.2 mg/ml
TargetCD49a
ImmunogenMouse Neuroblastoma Cell Line C1300
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD49a is a 1179 aa, type I transmembrane glycoprotein also known as α1 integrin, VLA-1 α chain, or integrin α1. It associates antibody v042010 with CD29 (β1 integrin) to form the VLA-1 complex, a collagen IV and alminin-1 receptor that is expressed on activated T cells, smooth muscle cells, endothelial cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration, T cell proliferation, and cytokine production.

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