PE/Cyanine7 anti-mouse IL-27Rα Antibody, IL-27Rα, W16125D,BioLegend,159005
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB016447717
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE/Cyanine7 anti-mouse IL-27Rα Antibody, IL-27Rα, W16125D
Cat. No.159005
HostRat
RRIDAB_2910326 (BioLegend Cat. No. 159005)AB_2910326 (BioLegend Cat. No. 159006)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberW16125D
Concentration0.2 mg/mL
TargetIL-27Ralpha
ImmunogenMouse IL-27Rα transfectant
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
69 kD glycosylated transmembrane subunit of IL-27 receptor complex consisting of IL27Ra (WSX-1, TCCR) and gp130 (CD130). Expressed on T cells, monocytes, and neutrophils and aside from its effect on innate immunity, is involved in dampening the extent of Th1 immune response post infection. Activity levels of INF-γ and IL-17 producing T cells are regulated through this receptor which relays signal through Jak-STAT pathway.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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