PE/Cyanine7 anti-mouse beta2-microglobulin Antibody anti-microglobulin - A16041A,BioLegend,154507

Beta 2-microglobulin (β2M) is a 12 kDa, Ig like, non-membrane-anchored glycoprotein. It non-covalently associates with MHC class I heavy chain and some Class I-like molecules and serves as the light chain. In association with MHC class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M plays an essential role in stabilizing MHC class I complexes for antigen presentation. In humans, circulating β2M levels are elevated in autoimmune/inflammatory disorders, viral infections, and glomerular filtration disorders.