PE/Cyanine7 anti-mouse/human CD207 (Langerin) Antibody, CD207, 4C7,BioLegend,144210
Host
Mouse
Reactivity
Mouse, Human
Application
FC -Quality tested
Platform ID
BAB061160038
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE/Cyanine7 anti-mouse/human CD207 (Langerin) Antibody, CD207, 4C7
Cat. No.144210
HostMouse
RRIDAB_2876490 (BioLegend Cat. No. 144209)AB_2876490 (BioLegend Cat. No. 144210)
IsotypeMouse IgG2a, κ
ReactivityMouse, Human
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number4C7
Concentration0.2 mg/mL
TargetCD207
ImmunogenLangerin extracellular domain-Fc fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD207, also known as langerin, is a 40 kD single-pass type II transmembrane protein, member of the C-type lectin family. CD207 is expressed on the cell surface and Birbeck granules (BGs) of Langerhans cells, and subsets of thymic and splenic dendritic cells. Its ligands are mannose,n-acetylglucosamine, fucose, and sulfated glycans. Langerin is involved in the antigen processing pathway through capture and internalization of its ligands.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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