PE/Cyanine7 anti-mouse lymphotoxin beta receptor LTbetaR Antibody anti-LTBR - 5G11,BioLegend,134410

Host

Rat

Reactivity

Mouse

Application

FC -Quality tested

Platform ID

BAB255200647

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePE/Cyanine7 anti-mouse lymphotoxin beta receptor LTbetaR Antibody anti-LTBR - 5G11
Cat. No.134410
HostRat
RRIDAB_2728152 (BioLegend Cat. No. 134409)AB_2728153 (BioLegend Cat. No. 134410)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number5G11
Concentration0.2 mg/ml
TargetLT-betaR
ImmunogenE.coliexpressed extracellular domain of mouse lymphotoxin beta receptor
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

LTβR is a type I transmembrane glycoprotein and member of the TNF receptor superfamily. It is a 61 KDa receptor for the mouse LTα1β2 and LIGHT. Northern blot analysis of tissues from adult mice showed that expression levels of LTβR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. It was reported that LTβR is expressed on stromal cells, monocytes, and certain embryonic epithelial layers. LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis.

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