PE/Cyanine7 anti-mouserat CD81 Antibody, CD81, Eat-2,BioLegend,104914

The Eat-2 antibody reacts with mouse and rat CD81. Additional reported applications (for the relevant formats) include: immunoprecipitation1,2, Western blotting1,2, induction of homotypic adhesion of B lymphocytes1, stimulation of B cells undergo early apoptotic events1, and promotion of T cell motility2.

Host

Armenian Hamster

Reactivity

Mouse, Rat

Application

FC -Quality tested

Platform ID

BAB783636991

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePE/Cyanine7 anti-mouserat CD81 Antibody, CD81, Eat-2
Cat. No.104914
HostArmenian Hamster
RRIDAB_2810339 (BioLegend Cat. No. 104913)AB_2810340 (BioLegend Cat. No. 104914)
IsotypeArmenian Hamster IgG1, κ
ReactivityMouse, Rat
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberEat-2
Concentration0.2 mg/ml
TargetCD81
ImmunogenCD81+ mouse B lymphoma 38C13
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1. CD81 is expressed on T and B cells, NK cells, dendritic cells, thymocytes, endothelial cells, and fibroblasts. CD81 induces B cell adhesion via the VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.

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