PE/Dazzle™ 594 anti-mouse CD16 Antibody, CD16, S17014E,BioLegend,158011

Anti-mouse CD16/32 clones 93 and 2.4G2 both block clone S17014E staining.

Host

Rat

Reactivity

Mouse

Application

FC -Quality tested

Platform ID

BAB193196630

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePE/Dazzle™ 594 anti-mouse CD16 Antibody, CD16, S17014E
Cat. No.158011
HostRat
RRIDAB_2876543 (BioLegend Cat. No. 158011)AB_2876543 (BioLegend Cat. No. 158012)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberS17014E
Concentration0.2 mg/mL
TargetCD16
ImmunogenMouse CD16 - transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD16 also know as Fcgr3 is a 50-65 kD type I transmembrane protein, member of the Fc gamma receptor family and  Ig superfamily. CD16  is expressed  on most myeloid cells including monocytes, macrophages, dendritic cells, and is also expressed by NK cells and NKT cells. CD16 is involved in cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC); its ligands are IgG1, IgG2a and IgG2b.

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