PE/Dazzle™ 594 anti-mouse GPR15/BOB Antibody, GPR15, S15042I,BioLegend,154610
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB128316523
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE/Dazzle™ 594 anti-mouse GPR15/BOB Antibody, GPR15, S15042I
Cat. No.154610
HostRat
RRIDAB_2910318 (BioLegend Cat. No. 154609)AB_2910318 (BioLegend Cat. No. 154610)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberS15042I
Concentration0.2 mg/mL
TargetGPR15/BOB
ImmunogenMouse GPR15-Transfectants
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
GPR15, also known as BOB, is a G-protein coupled receptor with 7 transmembrane regions that is present on the cell surface as a homotrimer. Its ligand, GPR15L, was recently identified. GPR15 is expressed by effector T cells and subsets of memory T cells, and is involved in the recruitment of proinflammatory CD4+T cells responsible of the pathogenesis in colitis. In humans, GPR15 acts as a receptor for human immunodeficiency virus (HIV) type 1 and 2, and is upregulated on monocytes and neutrophils in the synovia of patients with RA.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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