PE/Dazzle™ 594 anti-mouse VISTA (PD-1H) Antibody anti-VISTA - MIH63,BioLegend,150214
Host
Rat
Reactivity
Mouse
Application
FC -Quality tested
Platform ID
BAB755339316
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE/Dazzle™ 594 anti-mouse VISTA (PD-1H) Antibody anti-VISTA - MIH63
Cat. No.150214
HostRat
RRIDAB_2728193 (BioLegend Cat. No. 150213)AB_2728194 (BioLegend Cat. No. 150214)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberMIH63
Concentration0.2 mg/ml
TargetVISTA
ImmunogenMouse VISTA transfected J558 cells.
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
PD-1H, also known as VISTA, is a 309 aa type I transmembrane protein that is composed of seven exons. PD-1H has one Ig-V like domain, and its sequence is similar to the Ig-V domains of the members of CD28 and B7 families. PD-1H is expressed by a subset of T cells, macrophages, dendritic cells, neutrophils, and natural killer cells (NK). It has been proposed that PD-1H can be useful to modulate the host immune response to allogeneic transplants due to its ability to preferentially suppress CD4+T cell-mediated immunity.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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