PE/Fire™ 640 anti-human CD43 Antibody, CD43, CD43-10G7,BioLegend,343217

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB528314547

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePE/Fire™ 640 anti-human CD43 Antibody, CD43, CD43-10G7
Cat. No.343217
HostMouse
RRIDAB_3106024 (BioLegend Cat. No. 343217)AB_3106024 (BioLegend Cat. No. 343218)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberCD43-10G7
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD43
ImmunogenMV4-11 cell line
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Fire™ 640 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD43, also known as Ly-48, leukosialin, sialophorin, leukocyte sialoglycoprotein, and W3/13, is a large single chain, type I transmembrane glycoprotein with abundant O-glycosylation and sialylation sites. It has been reported that CD43 binds to CD54 and Siglec-1. CD43 plays dual roles in cell adhesion and anti-adhesion as well as costimulation of T cell activation and survival, and induction of apoptosis of T cells and hematopoietic progenitors.

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