PE/Fire™ 744 anti-mouse/human CD11b, CD11b, M1/70,BioLegend,101234
Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4,in vitroblocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. Forin vivostudies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).
Host
Rat
Reactivity
Mouse, Human, Cynomolgus, Rhesus
Application
FC - Quality tested
Platform ID
BAB872405626
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE/Fire™ 744 anti-mouse/human CD11b, CD11b, M1/70
Cat. No.101234
HostRat
RRIDAB_3106102 (BioLegend Cat. No. 101232)AB_3106102 (BioLegend Cat. No. 101234)
IsotypeRat IgG2b, κ
ReactivityMouse, Human, Cynomolgus, Rhesus
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberM1/70
Concentration0.2 mg/mL
TargetCD11b
ImmunogenC57BL/10 splenocytes
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Fire™ 744 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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