PE/Fire™ 810 anti-mouse CD3ε Recombinant Antibody, CD3ε, QA17A05,BioLegend,155719

Clone QA17A05 blocks clone 145-2C11. It also activates T cell proliferation like clone 145-2C11.

Host

Mouse

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB705352057

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePE/Fire™ 810 anti-mouse CD3ε Recombinant Antibody, CD3ε, QA17A05
Cat. No.155719
HostMouse
IsotypeMouse IgG1, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityRecombinant
Clone NumberQA17A05
Concentration0.2 mg/mL
TargetCD3epsilon
ImmunogenH-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Fire™ 810 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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