PE-Labeled Monoclonal Anti-Human CD279 (PD-1) Antibody, Mouse IgG2b (AS630) (0.03% Proclin),Acro Biosystems,FABm044-01
Host
Mouse
Conjugate
PE
Platform ID
BAB153169415
Acro Biosystems
Contact
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Product Specifications
Specifications
NamePE-Labeled Monoclonal Anti-Human CD279 (PD-1) Antibody, Mouse IgG2b (AS630) (0.03% Proclin)
Cat. No.FABm044-01
HostMouse
IsotypeMouse IgG2b | Mouse kappa
ConjugationPE
Clone NumberAS630
ImmunogenPurified Human CD279 Protein
FormulationSupplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.
Please contact us for customized product forms or formulations.
StorageCD279, or programmed cell death protein 1 (PD-1), is a 55 kD member of the immunoglobulin superfamily with an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic region. It is mainly expressed on activated T cells, B cells and myeloid cells, and negatively regulates immune responses by binding to its ligands PD-L1 (B7-H1) and PD-L2 (B7-DC), thereby inhibiting T cell proliferation and cytokine secretion. Dysregulatio of the PD-1 pathway is linked to autoimmune diseases (e.g, rheumatoid arthritis, systemic lupus erythematosus) and tumor immune escape, makin it a key target for cancer immunotherapy. The antibody PE, anti-Human CD279 (PD-1)-AS630 binds specifically to CD279, facilitating relevant research.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>Conjugated Antibodies
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