PE-Labeled Monoclonal Anti-Human TIM-3 Antibody, Rabbit IgG (M1G07) (0.03% Proclin),Acro Biosystems,FABm042-01
Monoclonal Anti-Human TIM-3 Antibody, Rabbit IgG (M1G07) is a rabbit monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which provides higher batch consistency and long term security of supply.
Host
Rabbit
Conjugate
PE
Platform ID
BAB217449810
Acro Biosystems
Contact
Tel: +1 800-810-0816
Fax:
Email:
Product Specifications
Specifications
NamePE-Labeled Monoclonal Anti-Human TIM-3 Antibody, Rabbit IgG (M1G07) (0.03% Proclin)
Cat. No.FABm042-01
HostRabbit
IsotypeRabbit IgG | Rabbit Kappa
ConjugationPE
Clone NumberM1G07
ImmunogenPurified Human TIM-3 Protein
FormulationSupplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.
Please contact us for customized product forms or formulations.
StorageHepatitis A virus cellular receptor 2 is also known as HAVCR2, FLJ14428, KIM3, TIM3, TIMD3, is a member of the TIM family of immune regulating molecules with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. HAVCR2 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice. HAVCR2 regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Dysregulation of the HAVCR2-galectin-9 pathway could underlie chronic autoimmune disease states in human, such as multiple sclerosis.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>Conjugated Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.