PE Rabbit anti-4-Hydroxynonenal/4-HNE mAb- ABclonal,ABclonal,A26084
Reactivity
Species independent
Application
FC (intra)
Conjugate
PE. Ex:565nm. Em:574nm.
Platform ID
BAB865075353
ABclonal
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Product Specifications
Scientific Background
Specifications
NamePE Rabbit anti-4-Hydroxynonenal/4-HNE mAb- ABclonal
Cat. No.A26084
RRID#N/A
IsotypeIgG
ReactivitySpecies independent
ConjugationPE. Ex:565nm. Em:574nm.
ApplicationFC (intra)
Working DilutionsFC (intra):5 μl per 10^6 cells in 100 μl volume
Clone NumberARC70314
ImmunogenChemical compounds corresponding to 4-Hydroxynonenal.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only
Scientific Background
4-hydroxy-2-nonenal (4-hydroxynonenal, 4-HNE) is a highly reactive aldehyde generated by the exposure of polyunsaturated fatty acids to peroxides and reactive oxygen species (ROS). It non-enzymatically forms stable protein adducts with histidine, lysine, and cysteine side chains that have been used as biomarkers for oxidative damage in cells. Conditions where 4-HNE immunoreactivity has been observed include include inflammation, neurodegenerative diseases, and ischemic damage to the heart and brain.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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