PE Rabbit anti-Human CD170/Siglec-5 mAb,ABclonal,A26119

Reactivity

Human

Application

FC

Conjugate

PE. Ex:565nm. Em:574nm.

Platform ID

BAB746809619

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NamePE Rabbit anti-Human CD170/Siglec-5 mAb
Cat. No.A26119
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationPE. Ex:565nm. Em:574nm.
ApplicationFC
Working DilutionsFC:5 μl per 10^6 cells in 100 μl volume
Clone NumberARC60966
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

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