PE Rabbit anti-Human CD221α/IGF-1Rα mAb,ABclonal,A28122
Reactivity
Human
Application
FC
Conjugate
PE. Ex:565nm. Em:574nm.
Platform ID
BAB430805052
ABclonal
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Product Specifications
Scientific Background
Specifications
NamePE Rabbit anti-Human CD221α/IGF-1Rα mAb
Cat. No.A28122
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationPE. Ex:565nm. Em:574nm.
ApplicationFC
Working DilutionsFC:5 μl per 10^6 cells in 100 μl volume
Clone NumberARC76079
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only
Scientific Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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