PE anti-IDO1 Antibody, IDO1, 2E2/IDO1,BioLegend,654006

Clone 2E2/IDO1 reacts with mouse IDO1. It does not appear to react with mouse IDO2.Clone 2E2/IDO1 is the same clone as anti-IDO1 clone 2E2.6.

Host

Mouse

Reactivity

Mouse

Application

ICFC - Quality tested

Platform ID

BAB427351768

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePE anti-IDO1 Antibody, IDO1, 2E2/IDO1
Cat. No.654006
HostMouse
RRIDAB_3097459 (BioLegend Cat. No. 654005)AB_3097459 (BioLegend Cat. No. 654006)
IsotypeMouse IgG1, κ
ReactivityMouse
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone Number2E2/IDO1
Concentration0.2 mg/mL
TargetIDO1
ImmunogenRecombinant mouse IDO1.
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

IDO1 is also known as Indolamine 2,3-dioxygenase, Indole 2,3-dioxygenase, and Indoleamine-pyrrole 2,3-dioxygenase. IDO is a ubiquitously expressed cytoplasmic protein with a predicted molecular weight of approximately 45 kD. Indoleamine 2,3-dioxygenase (IDO) is one the best known IFN-γ inducible genes. The product of IDO gene catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. IDO has been implicated to protect against intracellular and extracellular pathogens. It also has been shown to maintain the special immune suppressive status of immune-privileged sites such as the brain, eyes, kidney, and placenta.

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