PE anti-human Aiolos Antibody anti-Aiolos - 16D9C97,BioLegend,371103
NOTE: For flow cytometric staining with this clone, True-Nuclear™ Transcription Factor Buffer Set (Cat. No.424401) offers improved staining and is highly recommended.This clone is not recommended for ChIP (Chromatin Immunoprecipitation) assays (as determined by in-house testing).
Host
Mouse
Reactivity
Human
Application
ICFC - Quality tested
Platform ID
BAB793720884

BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NamePE anti-human Aiolos Antibody anti-Aiolos - 16D9C97
Cat. No.371103
HostMouse
RRIDAB_2572069 (BioLegend Cat. No. 371103)AB_2572070 (BioLegend Cat. No. 371104)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone Number16D9C97
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetAiolos
ImmunogenPartial Aiolos recombinant protein (1-130aa) expressed inE. Coli.
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Aiolos, also known as Ikaros family zinc finger 3 (IKZF3), is a 58kD zinc finger protein involved in hematopoetic-specific transcriptional activation. Aiolos is involved in regulation of gene expression in B lymphocytes through chromatin remodeling and formation of homodimers and heterodimers with other members of the Ikaros family. Deletion of Aiolos has been reported in pre-B-acute lymphocytic leukemia (B-ALL).
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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