PE anti-human CD108 Antibody, CD108, KS-2,BioLegend,376603

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB617782846

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePE anti-human CD108 Antibody, CD108, KS-2
Cat. No.376603
HostMouse
RRIDAB_2927888 (BioLegend Cat. No. 376603)AB_2927888 (BioLegend Cat. No. 376604)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberKS-2
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD108
ImmunogenPHA-activated PBMC
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD108 is an 80 kD GPI-linked membrane-bound semaphorin, also known as the John-Milton-Hagen (JMH) blood group antigen, semaphorin 7A, H-SEMA, and SEMAL. It contains an Ig-like domain and is expressed at low levels on erythrocytes and lymphocytes. The expression of CD108 on lymphocytes is upregulated upon activation, and it plays an important role in modulating inflammation and T-cell-mediated immune responses. CD108 is a guidance protein that is involved in central and peripheral axon growth. The interaction of CD108 with its receptor PlexinC1 induces activation of monocytes.

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