PE anti-human CD154 Antibody, CD154, W20199I,BioLegend,388204
Clone W20199I is able to block the binding of clone 24-31 on target cells.Clone W20199I is able to block the binding of CD40 and CD40L interaction on target cells.
Host
Rat
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB522794669
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NamePE anti-human CD154 Antibody, CD154, W20199I
Cat. No.388204
HostRat
RRIDAB_3105982 (BioLegend Cat. No. 388203)AB_3105982 (BioLegend Cat. No. 388204)
IsotypeRat IgG2b, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberW20199I
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD154
ImmunogenRecombinant human CD40L protein
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD154, also known as CD40L, TNFSF5, T-BAM, and gp39, is a 32-39 kD type II transmembrane glycoprotein member of the TNF superfamily expressed on activated T cells. CD154 interacts as a costimulatory molecule with CD40 on B Cells to induce B cell activation, resulting in proliferation, immunoglobulin production, and Ig Isotype switching. CD40L also may regulate T cell cytokine production.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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