PE anti-human CD20 Recombinant Antibody, CD20, QA18A14,BioLegend,389103

CD20, also known as B1 and Bp35, is a 33-37 kD four transmembrane spanning protein. CD20 is expressed on pre-B cells, resting B cells, and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.