PE anti-human CD229 Ly-9 Antibody anti-CD229 - HLy-9.1.25,BioLegend,326107
Additional reported (for the relevant formats) applications include: immunoprecipitation1,2, and immunocytochemistry3. The Ultra-LEAF™Purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 326109 & 326110).
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB297480343
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NamePE anti-human CD229 Ly-9 Antibody anti-CD229 - HLy-9.1.25
Cat. No.326107
HostMouse
RRIDAB_2137939 (BioLegend Cat. No. 326107)AB_2137938 (BioLegend Cat. No. 326108)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberHLy-9.1.25
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD229
Immunogen300.19 cell line transfected with the CD229 full-length DNA
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD229 is a 100-120 kD glycoprotein. It is a member of the SLAM family, a CD2 subset of the Ig superfamily, known as Ly9 or SLAMF3. CD229 is expressed on T cells, B cells, NK cells, and thymocytes. It functions as a homophilic adhesion molecule through binding to CD229 itself. The cytoplasmic tail of CD229 binds to SAP and Grb2 proteins. CD229 is involved in enhancing T cell activation and Th2 polarization. HLy9.1.25 antibody recognizes epitope A in the first Ig domain of Ly9 molecule.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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