PE anti-human CD275 (B7-H2, ICOSL) Antibody, CD275, W21036I,BioLegend,387503
Clone W21036I completely blocks clone 9F.8A4 but does not block clone 2D3.
Host
Rat
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB273469345
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE anti-human CD275 (B7-H2, ICOSL) Antibody, CD275, W21036I
Cat. No.387503
HostRat
RRIDAB_2941575 (BioLegend Cat. No. 387503)AB_2941575 (BioLegend Cat. No. 387504)
IsotypeRat IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberW21036I
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD275
ImmunogenHuman B7-H2 recombinant protein (19-258 aa)
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
B7-H2, a member of the B7 family and the immunoglobulin superfamily, is a 40 kD protein also known as B7RP-1, B7h, B7-H2, GL50 and ICOS Ligand. Human B7-H2 is expressed by B lymphocytes, activated monocytes/macrophages, and dendritic cells. B7-H2 binds to a CD28-like receptor, inducible costimulator molecule (ICOS, AILIM, CRP-1), which is expressed by activated T cells. The interaction of ICOS with B7-H2 plays an important role in the T cell costimulation pathway.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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