PE anti-human CD49a Antibody anti-CD49a - TS2/7,BioLegend,328303
Additional reported applications include: immunoprecipitation1, immunohistochemical staining1of acetone-fixed frozen tissue sections, and spatial biology (IBEX)3,4.
Host
Mouse
Reactivity
Human
Application
FC - Quality testedSB - Reported in the literature, not verified in house
Platform ID
BAB658863118

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Product Specifications
Scientific Background
Specifications
NamePE anti-human CD49a Antibody anti-CD49a - TS2/7
Cat. No.328303
HostMouse
RRIDAB_1236441 (BioLegend Cat. No. 328303)AB_1236407 (BioLegend Cat. No. 328304)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality testedSB - Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberTS2/7
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD49a
ImmunogenHuman CTL line
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD49a is a 200 kD type I transmembrane glycoprotein also known as α1integrin, VLA-1 α chain, or Integrin α1. It associates with CD29 (β1integrin) to form VLA-1 complex, a collagen IV and alminin-1 receptor. It is expressed on activated T cells, monocytes, NK cells, smooth muscle cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration, T cell proliferation, and cytokine production.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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