PE anti-human CD49a Antibody anti-CD49a - TS2/7,BioLegend,328303

Additional reported applications include: immunoprecipitation1, immunohistochemical staining1of acetone-fixed frozen tissue sections, and spatial biology (IBEX)3,4.

Host

Mouse

Reactivity

Human

Application

FC - Quality testedSB - Reported in the literature, not verified in house

Platform ID

BAB658863118

BioLegend

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePE anti-human CD49a Antibody anti-CD49a - TS2/7
Cat. No.328303
HostMouse
RRIDAB_1236441 (BioLegend Cat. No. 328303)AB_1236407 (BioLegend Cat. No. 328304)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality testedSB - Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberTS2/7
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD49a
ImmunogenHuman CTL line
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD49a is a 200 kD type I transmembrane glycoprotein also known as α1integrin, VLA-1 α chain, or Integrin α1. It associates with CD29 (β1integrin) to form VLA-1 complex, a collagen IV and alminin-1 receptor. It is expressed on activated T cells, monocytes, NK cells, smooth muscle cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration, T cell proliferation, and cytokine production.

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